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AM-2201

200 $1150 $

CAS Number: 870003-24-4
Molecular Formula: C21H22FNO
Molar Mass: 319.41 g/mol

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Description

Buy AM-2201 Online in USA

Chemical Name: 1-(5-Fluoropentyl)-3-(1-naphthoyl)indole
Form: Powder
Molecular Formula: C21H22FNO
Molar Mass: 319.41 g/mol
IUPAC: 1-(5-fluoropentyl)-3-(naphthalen-1-ylcarbonyl)indole
CAS Number: 870003-24-4
Active Ingredient: AM-2201 (99% purity)
Other Ingredients: None

AM-2201 for Sale

Buy AM-2201 online is a synthetic cannabinoid that mimics the effects of THC by binding to cannabinoid receptors in the brain. It is used in research to study cannabinoid receptor interactions and the psychoactive effects of synthetic cannabinoids. Its potent effects make it a valuable compound for exploring cannabinoid mechanisms.

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AM-2201, or 1-(5-fluoropentyl)-3-(1-naphthoyl)indole, has a strong affinity for CB1 and CB2 receptors, producing effects similar to those of natural cannabinoids, such as altered perception and euphoria. However, its use can lead to significant side effects, including anxiety, paranoia, and cardiovascular issues, particularly when misused.

Due to its potent psychoactive effects and potential for abuse, buy AM-2201 online is regulated in many regions, and its use is restricted to research purposes. Adhering to all legal and safety guidelines is essential when handling this compound. AM-2201 is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor. It is part of the AM series of cannabinoids discovered by Alexandros Makriyannis at Northeastern University.

We evaluated the inhibitory effect of AM-2201 on the activities of eight major human CYPs (1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, and 3A4) and six major human UGTs (1A1, 1A3, 1A4, 1A6, 1A9, and 2B7) enzymes in pooled human liver microsomes using liquid chromatography–tandem mass spectrometry to investigate drug interaction potentials of AM-2201.

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AM-2201 potently inhibited CYP2C9-catalyzed diclofenac 4′-hydroxylation, CYP3A4-catalyzed midazolam 1′-hydroxylation, UGT1A3-catalyzed chenodeoxycholic acid 24-acyl-glucuronidation, and UGT2B7-catalyzed naloxone 3-glucuronidation with IC50 values of 3.9, 4.0, 4.3, and 10.0 µM, respectively, and showed mechanism-based inhibition of CYP2C8-catalyzed amodiaquine N-deethylation with a Ki value of 2.1 µM.

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